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Vol. 99. Issue 3.
Pages 173-184 (April 2008)
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Vol. 99. Issue 3.
Pages 173-184 (April 2008)
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Smoking and the Skin
Hábito de Fumar y Piel
Visits
7674
M. Just-Sarobé
Corresponding author
mjust@wanadoo.es

Correspondence: Servei de Dermatologia, Fundació Salut Empordà, Hospital de Figueres, Ronda Rector Arolas, s/n, 17600 Figueres, Girona, Spain.
Servei de Dermatologia, Fundació Salut Empordà, Hospital de Figueres, Gerona, Spain
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Abstract

Smoking is the main modifiable cause of disease and death in the developed world. Tobacco consumption is directly linked to cardiovascular disease, chronic bronchitis, and many malignant diseases. Tobacco also has many cutaneous effects, most of which are harmful. Smoking is closely associated with several dermatologic diseases such as psoriasis, pustulosis palmoplantaris, hidrosadenitis suppurativa, and systemic and discoid lupus erythematosus, as well as cancers such as those of the lip, oral cavity, and anogenital region. A more debatable relationship exists with melanoma, squamous cell carcinoma of the skin, basal cell carcinoma, and acne. In contrast, smoking seems to protect against mouth sores, rosacea, labial herpes simplex, pemphigus vulgaris, and dermatitis herpetiformis. In addition to the influence of smoking on dermatologic diseases, tobacco consumption is also directly responsible for certain dermatoses such as nicotine stomatitis, black hairy tongue, periodontal disease, and some types of urticaria and contact dermatitis. Furthermore, we should not forget that smoking has cosmetic repercussions such as yellow fingers and fingernails, changes in tooth color, taste and smell disorders, halitosis and hypersalivation, and early development of facial wrinkles.

Key words:
tobacco
smoking
skin
aging
Resumen

El hábito de fumar constituye la principal causa evitable de enfermedad y muerte en el mundo occidental. Su consumo se relaciona directamente con enfermedades cardiovasculares, bronquitis crónica y numerosos procesos neoplásicos. El tabaco ejerce asimismo múltiples y diversos efectos sobre la piel, la mayor parte de ellos nocivos. En este sentido, el hábito de fumar se halla estrechamente relacionado con numerosas enfermedades dermatológicas como la psoriasis, la pustulosis palmoplantar, la hidrosadenitis supurativa, el lupus eritematoso sistémico y discoide, así como con procesos neoplásicos del labio, de la cavidad oral y de la región anogenital, entre otros. Existe una relación controvertida con el melanoma, el carcinoma escamoso de la piel, el carcinoma basocelular y el acné. Por otra parte, este hábito parece que ejercería un efecto protector frente al desarrollo de las aftas orales, de la rosácea, del herpes simple labial, del pénfigo vulgar y de la dermatitis herpetiforme. Aparte de la influencia que el hábito de fumar ejerce sobre las enfermedades dermatológicas, el consumo de tabaco es también responsable directo de distintas dermatosis como la estomatitis nicotínica, la lengua negra vellosa, la enfermedad periodontal, así como de algunos tipos de urticaria y de dermatitis de contacto. Además, no hay que olvidar la repercusión cosmética de este hábito, que conlleva una pigmentación amarilla de los dedos y de las uñas, una alteración del color normal de los dientes, una disminución del gusto y del olfato, halitosis e hipersalivación y un desarrollo precoz de arrugas faciales.

Palabras clave:
tabaco
fumar
piel
envejecimiento
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References
[1.]
C.M. Mills, E.D. Srivastava, I.M. Harvey, G.L. Swift, R.G. Newcombe, P.J.A. Holt, et al.
Smoking habits in psoriasis: a case control study.
Br J Dermatol, 127 (1992), pp. 18-21
[2.]
M.D. Herron, M. Hinckley, M.S. Hoffman, J. Papenfuss, C.B. Hansen, K.P. Callis, et al.
Impact of obesity and smoking on psoriasis presentation and management.
Arch Dermatol, 141 (2005), pp. 1527-1534
[3.]
L.R. Braathen, G. Botten, T. Bjerkedal.
Psoriasis in Norway: a questionnaire study of health status, contact with paramedical professions and alcohol and tobacco consumption.
Acta Dermatol Venerol (Stockh), 142 (1989), pp. 9-12
[4.]
L. Naldi.
Cigarette smoking and psoriasis.
Clinics in Dermatol, 16 (1998), pp. 571-574
[5.]
L. Naldi, L. Chatenoud, D. Linder, A. Belloni, A. Peserico, A.R. Virgili, et al.
Cigarette smoking, body mass index, and stressful life events as risk factors for psoriasis: results from an Italian case-control study.
J Invest Dermatol, 125 (2005), pp. 61-67
[6.]
S.M. Behnam, S.E. Behnam, J.Y. Koo.
Smoking and psoriasis.
Skinmed, 4 (2005), pp. 174-176
[7.]
L. Naldi, F. Parazzini, A. Brevi, A. Peserico, C. Vellver, G. Grosso, et al.
Family history, smoking habits, alcohol consumption and risk of psoriasis.
Br J Dermatol, 127 (1992), pp. 212-217
[8.]
C. Fortes, S. Mastroeni, K. Leffondre, F. Sampogna, F. Melchi, E. Mazzotti, et al.
Relationship between smoking and the clinical severity of psoriasis.
Arch Dermatol, 141 (2005), pp. 1580-1584
[9.]
T.S. Sonnex, P. Carrington, P. Norris, M.W. Greaves.
Polymorphonuclear leukocyte random migration and chemotaxis in psoriatic and healthy adult smokers and non-smokers.
Br J Dermatol, 119 (1988), pp. 653-659
[10.]
C.J. O’Doherty, C. Macintyre.
Palmoplantar pustulosis and smoking.
BMJ, 291 (1985), pp. 861-864
[11.]
M.O. Eriksson, E. Hagforsen, I.P. Lunding, G. Michaelsson.
Palmoplantar pustulosis: a clinical and immunohistological study.
Br J Dermatol, 138 (1998), pp. 390-398
[12.]
G. Michaëlsson, K. Gustafsson, E. Hagforsen.
The psoriasis variant palmoplantar pustulosis can be improved after cessation of smoking.
J Am Acad Dermatol, 54 (2006), pp. 737-738
[13.]
E. Hagforsen, M. Awder, A.K. Lefvert, K. Nordlind, G. Michaëlsson.
Palmoplantar pustulosis: an autoimmune disease precipitated by smoking?.
Acta Derm Venereol, 82 (2002), pp. 341-346
[14.]
R. Giménez-García, S. Sánchez-Ramón, L.A. Cuéllar-Olmedo.
Palmoplantar pustulosis: a clinicoepidemiological study. The relationship between tobacco use and thyroid function.
J Eur Acad Dermatol Venereol, 17 (2003), pp. 276-279
[15.]
S. Silverman, M. Gorsky, F. Lozada-Nur, A. Liu.
Oral mucous membrane pemphigoid. A study of sixty-five patients.
Oral Surg Oral Med Oral Pathol, 61 (1986), pp. 233-237
[16.]
M. Alexandre, M.D. Brette, F. Pascal, P. Tsianakas, S. Fraitag, S. Doan, et al.
A prospective study of upper aerodigestive tract manifestations of mucous membrane pemphigoid.
Medicine (Baltimore), 85 (2006), pp. 239-252
[17.]
M. Valikhani, S. Kavusi, C. Chams-Davatchi, M. Daneshpazhooh, M. Barzegari, M. Ghiasi, et al.
Pemphigus and associated environmental factors: a casecontrol study.
Clin Exp Dermatol, 32 (2007), pp. 256-260
[18.]
S. Brenner, E. Tur, J. Shapiro, V. Ruocco, M. D’Avino, E. Ruocco, et al.
Pemphigus vulgaris: environmental factors. Occupational, behavioral, medical, and qualitative food frequency questionnaire.
Int J Dermatol, 40 (2001), pp. 562-569
[19.]
J.N. Mehta, A.G. Martin.
A case of pemphigus vulgaris improved by cigarette smoking.
Arch Dermatol, 136 (2000), pp. 15-17
[20.]
S. Suman, E.J. Williams, P.W. Thomas, S.L. Surgenor, J.A. Snook.
Is the risk of adult coeliac disease causally related to cigarette exposure?.
Eur J Gastroenterol Hepatol, 15 (2003), pp. 995-1000
[21.]
A.S. Austin, R.F. Logan, K. Thomason, G.K. Holmes.
Cigarette smoking and adult coeliac disease.
Scand J Gastroenterol, 37 (2002), pp. 978-982
[22.]
J.A. Snook, L. Dwyer, C. Lee-Elliott, S. Khan, D.W. Wheeler, D.S. Nicholas.
Adult coeliac disease and cigarette smoking.
Gut, 39 (1996), pp. 60-62
[23.]
J.T. Lear, J.S. English, P.W. Jones.
Adult coeliac disease, dermatitis herpetiformis and smoking.
Gut, 40 (1997), pp. 289
[24.]
J.B. Smith, S.B. Smith, J.J. Zone.
Dermatitis herpetiformis and cigarette smoking.
Gut, 43 (1998), pp. 732
[25.]
S. Prasad, P. Thomas, D.S. Nicholas, N.M. Sharer, J.A. Snook.
Adult endomysial antibody-negative coeliac disease and cigarette smoking.
Eur J Gastroenterol Hepatol, 13 (2001), pp. 667-671
[26.]
S.A. McMillan, S.D. Johnston, R.G. Watson, H.J. Ellis, P.J. Ciclitira, E.E. McCrum, et al.
Dietary intake, smoking, and transient anti-gliadin antibodies.
Scand J Gastroenterol, 33 (1998), pp. 499-503
[27.]
P. Silverstein.
Smoking and wound healing.
Am J Med, 93 (1992), pp. 22S-24S
[28.]
J.E. Siana, S. Rex, F. Gottrup.
The effect of cigarette smoking on wound healing.
Scand J Plast Reconstr Surg, 23 (1989), pp. 207-209
[29.]
R. Wolf, A. Lo Schiavo, V. Ruocco.
Smoking out the skin.
J Appl Cosmetol, 13 (1995), pp. 1-14
[30.]
R. Riefkohl, J.A. Wolfe, E.B. Cox, K.S. McCarty Jr.
Association between cutaneous occlusive vascular disease, cigarette smoking, and skin slough after rhytidectomy.
Plast Reconstr Surg, 77 (1986), pp. 592-595
[31.]
J.B. Kinsella, C.H. Rassekh, Z.D. Wassmuth, J.A. Hokanson, K.H. Calhoun.
Smoking increases facial skin flap complications.
Ann Otol Rhinol Laryngol, 108 (1999), pp. 139-142
[32.]
D. Goldminz, R.G. Bennet.
Cigarette smoking and flap and full-thickness graft necrosis.
Arch Dermatol, 127 (1991), pp. 1012-1015
[33.]
J.B. Smith, N.A. Fenske.
Cutaneous manifestations and consequences of smoking.
J Am Acad Dermatol, 34 (1996), pp. 717-732
[34.]
A. Møller, H. Tønnesen.
Risk reduction: perioperative smoking intervention.
Best Pract Res Clin Anaesthesiol, 20 (2006), pp. 237-248
[35.]
P.A. Newcomb, P.P. Carbone.
The health consequences of smoking. Cancer.
Med Clin North Am, 76 (1992), pp. 305-331
[36.]
A. Osterlind, M.A. Tucker, B.J. Stone, O.M. Jensen.
The Danish case-control study of cutaneous malignant melanoma. IV. No association with nutritional factors, alcohol, smoking or hair dyes.
Int J Cancer, 42 (1988), pp. 825-828
[37.]
J. Westerdahl, H. Olsson, A. Masbäck, C. Ingvar, N. Jonsson.
Risk of malignant melanoma in relation to drug intake, alcohol, smoking and hormonal factors.
Br J Cancer, 73 (1996), pp. 1126-1131
[38.]
H.M. Shaw, G.W. Milton.
Smoking and the development of metastases from malignant melanoma.
Int J Cancer, 28 (1981), pp. 153-156
[39.]
H.K. Koh, A.J. Sober, C.L. Day, R.A. Lew, T.B. Fitzpatrick.
Cigarette smoking and malignant melanoma. Prognostic implications.
Cancer, 53 (1984), pp. 2570-2573
[40.]
D.S. Rigel, R.J. Friedman, J. Levine, A.W. Kopf, M. Levenstein.
Cigarette smoking and malignant melanoma.
J Dermatol Surg Oncol, 7 (1981), pp. 889-891
[41.]
J. Siemiatycki, D. Krewski, E. Franco, M. Kaiserman.
Association between cigarette smoking and each of 21 types of cancer: a multi-site case-control study.
Int J Epidemiol, 24 (1995), pp. 504-514
[42.]
D.M. Freedman, A. Sigurdson, M.M. Doody, R.S. Rao, M.S. Linet.
Risk of melanoma in relation to smoking, alcohol intake, and other factors in a large occupational cohort.
Cancer Causes Control, 14 (2003), pp. 847-857
[43.]
A. Odenbro, P. Gillgren, R. Bellocco, P. Boffetta, N. Hakansson, J. Adami.
The risk for cutaneous malignant melanoma, melanoma in situ and intraocular malignant melanoma in relation to tobacco use and body mass index.
Br J Dermatol, 156 (2007), pp. 99-105
[44.]
J.T. Lear, B.B. Tan, A.G. Smith, P.W. Jones, A.H. Heagerty, R.C. Strange, et al.
A comparison of risk factors for malignant melanoma, squamous cell carcinoma and basal cell carcinoma in the UK.
Int J Clin Pract, 52 (1998), pp. 145-149
[45.]
F. Aubry, B. MacGibbon.
Risk factors of squamous cell carcinoma of the skin.
Cancer, 55 (1985), pp. 907-911
[46.]
F. Grodstein, F.E. Speizer, D.J. Hunter.
A prospective study of incident squamous cell carcinoma of the skin in the Nurses Health Study.
J Natl Cancer Inst, 87 (1995), pp. 1061-1066
[47.]
M.R. Karagas, T.A. Stukel, E.R. Greenberg, J.A. Baron, L.A. Mott, R.S. Stern.
Risk of subsequent basal cell carcinoma and squamous cell carcinoma of the skin among patients with prior skin cancer. Skin Cancer Prevention Study Group.
JAMA, 267 (1992), pp. 3305-3310
[48.]
S.A. De Hertog, C.A. Wensveen, M.T. Bastiaens, C.J. Kielich, M.J. Berkhout, R.G. Westendorp, Leiden Skin Cancer Study, et al.
Relation between smoking and skin cancer.
J Clin Oncol, 19 (2001), pp. 231-238
[49.]
G.A. Kune, S. Bannerman, L.F. Watson, H. Cleland, D. Merenstein, L. Vitetta.
Diet, alcohol, smoking, serum beta-carotene, and vitamin A in male nonmelanocytic skin cancer patients and controls.
Nutr Cancer, 18 (1992), pp. 237-244
[50.]
D.J. Hogan, P.R. Lane, L. Gran, D. Wong.
Risk factors for squamous cell carcinoma of the skin in Saskatchewan, Canada.
J Dermatol Sci, 1 (1990), pp. 97-101
[51.]
L. Molnar, P. Ronay, L. Tapolcsani.
Carcinoma of the lip: analysis of the material of 25 years.
Oncology, 29 (1974), pp. 101-121
[52.]
K. Jorgensen, O. Elbrond, A.D. Andersen.
Carcinoma of the lip: a series of 869 cases.
Acta Radiol, 12 (1973), pp. 177-190
[53.]
E. Ratzkowski, A. Hochman, A. Buchner, J. Michman.
Causes of cancer of the lip: review of 167 cases.
Oncologia, 20 (1966), pp. 129-144
[54.]
E. Perea- Milla, R.M. Miñarro-del Moral, C. Martínez-García, R. Zanetti, S. Rosso, S. Serrano, et al.
Lifestyles, environmental and phenotypic factors associated with lip cancer: a case-control study in southern Spain.
Br J Cancer, 88 (2003), pp. 1702-1707
[55.]
G.N. King, C.M. Healy, M.T. Glover, J.T.C. Kwan, D.M. Williams, I.M. Leigh, et al.
Increased prevalence of dysplastic and malignant lip lesions in renal transplant recipients.
N Engl J Med, 332 (1995), pp. 1052-1057
[56.]
W.J. Blot, J.K. McLaughlin, D.M. Winn, D.F. Austin, R.S. Greenberg, S. Preston-Martin, et al.
Smoking and drinking in relation to oral and pharyngeal cancer.
Cancer Res, 48 (1988), pp. 3282-3287
[57.]
T. Takezaki, K. Hirose, M. Inoue, N. Hamajima, T. Kuroishi, S. Nakamura, et al.
Tobacco, alcohol and dietary factors associated with the risk of oral cancer among Japanese.
Jpn J Cancer Res, 6 (1996), pp. 555-562
[58.]
S. Franceschi, S. Barra, C. La Vecchia, E. Bidoli, E. Negri, R. Talamini.
Risk factors for cancer of the tongue and the mouth: a case-control study from northern Italy.
Cancer, 70 (1992), pp. 2227-2233
[59.]
E.L. Franco, L.P. Kowalski, B.V. Oliveira, M.P. Curado, R.N. Pereira, M.E. Silva, et al.
Risk factors for oral cancer in Brazil: a case-control study.
Int J Cancer, 43 (1989), pp. 992-1000
[60.]
D.R. Shopland.
Tobacco use and its contribution to early cancer mortality with a special emphasis on cigarette smoking.
Environ Health Perspect, 103 (1995), pp. 131-142
[61.]
J.E. Muscat, J.P. Richie Jr, S. Thompson, E.L. Wynder.
Gender differences in smoking and risk for oral cancer.
Cancer Res, 56 (1996), pp. 5192-5197
[62.]
G.C. Kabat, C.J. Chang, E.L. Wynder.
The role of tobacco, alcohol use, and body mass index in oral and pharyngeal cancer.
Int J Epidemiol, 23 (1994), pp. 1137-1144
[63.]
S.Y. Choy, H. Kahyo.
Effect of cigarette smoking and alcohol consumption in the aetiology of cancer of the oral cavity, pharynx and larynx.
Int J Epidemiol, 20 (1991), pp. 878-885
[64.]
T. Zheng, T. Holford, Y. Chen, P. Jiang, B. Zhang, P. Boyle.
Risk of tongue cancer associated with tobacco smoking and alcohol consumption: a case-control study.
Oral Oncol, 33 (1997), pp. 82-85
[65.]
P.C. Gupta, P.R. Murti, R.B. Bhonsle, F.S. Mehta, J.J. Pindborg.
Effect of cessation of tobacco use on the incidence of oral mucosal lesions in a 10-yr follow-up study of 12,212 users.
Oral Dis, 1 (1995), pp. 54-58
[66.]
N. Johnson.
Tobacco use and oral cancer: a global perspective.
J Dent Educ, 65 (2001), pp. 328-339
[67.]
N.K. Proia, G.M. Paszkiewicz, M.A. Sullivan, G.E. Franke, J.L. Pauly.
Smoking and smokeless tobacco-associated human buccal cell mutations and their association with oral cancer-A Review.
Cancer Epidemiol Biomarkers Prev, 15 (2006), pp. 1061-1077
[68.]
J.R. Daling, K.J. Sherman, T.G. Hislop, C. Maden, M.T. Mandelson, A.M. Beckmann, et al.
Cigarette smoking and the risk of anogenital cancer.
Am J Epidemiol, 135 (1992), pp. 180-189
[69.]
T.O. Moore, A.Y. Moore, D. Carrasco, M. Vander Straten, I. Arany, W. Au, et al.
Human papillomavirus, smoking, and cancer.
J Cutan Med Surg, 5 (2001), pp. 323-328
[70.]
D. Hellberg, J. Valentin, T. Eklund, S. Nilsson.
Penile cancer: is there an epidemiological role for smoking and sexual behaviour?.
Br Med J (Clin Res Ed), 295 (1987), pp. 1306-1308
[71.]
K. Harish, R. Ravi.
The role of tobacco in penile carcinoma.
Br J Urol, 75 (1995), pp. 375-377
[72.]
J.R. Daling, M.M. Madeleine, L.G. Johnson, S.M. Schwartz, K.A. Shera, M.A. Wurscher, et al.
Penile cancer: importance of circumcision, human papillomavirus and smoking in in situ and invasive disease.
Int J Cancer, 116 (2005), pp. 606-616
[73.]
R. Zarcone, G. Mainini, E. Carfora, A. Cardone.
Current etiopathogenetic views in vulvar cancer.
Panminerva Med, 39 (1997), pp. 30-34
[74.]
C.V. Kirschner, E.L. Yordan, K. De Geest, G.D. Wilbanks.
Smoking, obesity, and survival in squamous cell carcinoma of the vulva.
Gynecol Oncol, 56 (1995), pp. 79-84
[75.]
J. Kouvaris, V. Kouloulias, C. Loghis, C. Sykiotis, M. Balafouta, L. Vlahos.
Prognostic factors for survival in invasive squamous cell vulvar carcinoma: a univariate analysis.
Gynecol Obstet Invest, 51 (2001), pp. 262-265
[76.]
L.A. Brinton, P.C. Nasca, K. Mallin, M.S. Baptiste, G.D. Wilbanks, R.M. Richart.
Case-control study of cancer of the vulva.
Obstet Gynecol, 75 (1990), pp. 859-866
[77.]
A.S. Boyd, Y. Shyr, L.E. King.
Basal cell carcinoma in young women: an evaluation of the association of tanning bed use and smoking.
J Am Acad Dermatol, 46 (2002), pp. 706-709
[78.]
T.H. Wojno.
The association between cigarette smoking and basal cell carcinoma of the eyelids in women.
Ophtal Plast Reconstr Surg, 15 (1999), pp. 390-392
[79.]
T. Milán, P.K. Verkasalo, J. Kaprio, M. Koskenvuo.
Lifestyle differences in twin pairs discordant for basal cell carcinoma of the skin.
Br J Dermatol, 149 (2003), pp. 115-123
[80.]
Z. Erbagci, S. Erkilic.
Can smoking and/or occupational UV exposure have any role in the development of the morpheaform basal cell carcinoma? A critical role for paritumoral mast cells.
Int J Dermatol, 41 (2002), pp. 275-278
[81.]
D.M. Freedman, A. Sigurdson, M.M. Doody, K. Mabuchi, M.S. Linet.
Risk of basal cell carcinoma in relation to alcohol intake and smoking.
Cancer Epidemiol Biomarkers Prev, 12 (2003), pp. 1540-1543
[82.]
R.M. Van Dam, Z. Huang, E.B. Rimm, M.A. Weinstock, D. Spiegelman, G.A. Colditz, et al.
Risk factors for basal cell carcinoma of the skin in men: results from the health professionals follow-up study.
Am J Epidemiol, 150 (1999), pp. 459-468
[83.]
R. Corona, E. Dogliotti, M. D’Errico, F. Sera, I. Iavarone, G. Baliva, et al.
Risk factors for basal cell carcinoma in a Mediterranean population.
Arch Dermatol, 137 (2001), pp. 1162-1168
[84.]
S. Shapiro, D.L. Olson, S.J. Chellemi.
The association between smoking and aphthous ulcers.
Oral Surg, 30 (1970), pp. 624-630
[85.]
L. Salonen, T. Axéll, L. Helldén.
Occurrence of oral lesions, the influence of tobacco habits and an estimate of treatment time in an adult Swedish population.
J Oral Pathol Med, 19 (1990), pp. 170-176
[86.]
D. Grady, V.L. Ernster, L. Stillman, J. Greenspan.
Smokeless tobacco use prevents aphthous stomatitis.
Oral Surg Oral Med Oral Pathol, 74 (1992), pp. 463-465
[87.]
J.A. Baron.
Beneficial effects of nicotine and cigarette smoking: the real, the possible and the spurious.
Br Med Bull, 52 (1996), pp. 58-73
[88.]
C.M. Mills, T.J. Peters, A.Y. Finlay.
Does smoking influence acne?.
Clin Exp Dermatol, 18 (1993), pp. 100-101
[89.]
I. Klaz, I. Kochba, T. Shohat, S. Zarka, S. Brenner.
Severe acne vulgaris and tobacco smoking in young men.
J Invest Dermatol, 126 (2006), pp. 1749-1752
[90.]
S. Rombouts, T. Nijsten, J. Lambert.
Cigarette smoking and acne in adolescents: results from a cross-sectional study.
J Eur Acad Dermatol Venereol, 21 (2007), pp. 326-333
[91.]
A. Firooz, R. Sarhangnejad, S.M. Davoudi, M. Nassiri-Kashani.
Acne and smoking: is there a relationship?.
BMC Dermatol, 5 (2005), pp. 2
[92.]
T. Schäfer, A. Nienhaus, D. Vieluf, J. Berger, J. Ring.
Epidemiology of acne in the general population: the risk of smoking.
Br J Dermatol, 145 (2001), pp. 100-104
[93.]
A.A. Chuh, V. Zawar, W.C. Wong, A. Lee.
The association of smoking and acne in men in Hong Kong and in India: a retrospective case-control study in primary care settings.
Clin Exp Dermatol, 29 (2004), pp. 597-599
[94.]
C.M. Mills, R. Marks.
Environmental factors influencing rosacea.
Clin Exp Dermatol, 21 (1996), pp. 172-173
[95.]
A. König, C. Lehman, R. Rompel, R. Happle.
Cigarette smoking as a triggering factor of hidradenitis suppurativa.
Dermatology, 198 (1999), pp. 261-264
[96.]
L.K. Dotterud, T. Smith-Sivertsen.
Allergic contact sensitization in the general adult population: a population-based study from Northern Norway.
Contact Dermatitis, 56 (2007), pp. 10-15
[97.]
P. Montnémery, U. Nihlén, C.G. Löfdahl, P. Nyberg, A. Svensson.
Prevalence of hand eczema in an adult Swedish population and the relationship to risk occupation and smoking.
Acta Derm Venereol, 85 (2005), pp. 429-432
[98.]
A. Linneberg, N.H. Nielsen, T. Menné, F. Madsen, T. Jørgensen.
Smoking might be a risk factor for contact allergy.
J Allergy Clin Immunol, 111 (2003), pp. 980-984
[99.]
C.M. Mills, E.D. Srivastava, I.M. Harvey, G.L. Swift, R.G. Newcombe, P.J.A. Holt, et al.
Cigarette smoking is not a risk factor in atopic dermatitis.
Int J Dermatol, 33 (1994), pp. 33-34
[100.]
K.H. Costenbader, E.W. Karlson.
Cigarette smoking and autoimmune disease: what can we learn from epidemiology?.
Lupus, 15 (2006), pp. 737-745
[101.]
L. Klareskog, L. Padyukov, L. Alfredsson.
Smoking as a trigger for inflammatory rheumatic diseases.
Curr Opin Rheumatol, 19 (2007), pp. 49-54
[102.]
M. Washio, T. Horiuchi, C. Kiyohara, H. Kodama, Y. Tada, T. Asami, et al.
Smoking, drinking, sleeping habits, and other lifestyle factors and the risk of systemic lupus erythematosus in Japanese females: findings from the KYSS study.
Mod Rheumatol, 16 (2006), pp. 143-150
[103.]
K.H. Costenbader, E.W. Karlson.
Cigarette smoking and systemic lupus erythematosus: a smoking gun?.
Autoimmunity, 38 (2005), pp. 541-547
[104.]
H.A. Miot, L.D. Bartoli Miot, G.R. Haddad.
Association between discoid lupus erythematosus and cigarette smoking.
Dermatology, 211 (2005), pp. 118-122
[105.]
C. Nagata, S. Fujita, H. Iwata, Y. Kurosawa, M. Kobayashi.
Systemic lupus erythematosus: a case-control epidemiologic study in Japan.
Int J Dermatol, 34 (1995), pp. 333-337
[106.]
G.C. Keough, R.A. Laws, D.M. Elston.
Favre-Racouchot syndrome: a case for smokers’ comedones.
Arch Dermatol, 133 (1997), pp. 796-797
[107.]
J.L. Xue, M.W. Fan, S.Z. Wang, X.M. Chen, Y. Li, L. Wang.
A clinical study of 674 patients with oral lichen planus in China.
J Oral Pathol Med, 34 (2005), pp. 467-472
[108.]
S. Silverman, S. Bahl.
Oral lichen planus update: clinical characteristics, treatment responses, and malignant transformation.
Am J Dent, 10 (1997), pp. 259-263
[109.]
S. Silverman, M. Gorsky, F. Lozada-Nur, K. Giannotti.
A prospective study of findings and management in 214 patients with oral lichen planus.
Oral Surg Oral Med Oral Pathol, 72 (1991), pp. 665-670
[110.]
T. Axéll, R. Liedholm.
Occurrence of recurrent herpes labiales in an adult Swedish population.
Acta Odontol Scand, 48 (1990), pp. 119-123
[111.]
R. Wolf, D. Wolf, V. Ruocco.
The benefits of smoking in skin diseases.
Clinics in Dermatol, 16 (1998), pp. 641-647
[112.]
G. Taybos.
Oral changes associated with tobacco use.
Am J Med Sci, 326 (2003), pp. 179-182
[113.]
S.M. Mirbod, S.I. Ahing.
Tobacco-associated lesions of the oral cavity: Part I. Nonmalignant lesions.
J Can Dent Assoc, 66 (2000), pp. 252-256
[114.]
S.J. Meraw, I.Z. Mustapha, R.S. Rogers.
Cigarette smoking and oral lesions other than cancer.
Clin Dermatol, 16 (1998), pp. 625-631
[115.]
G. Pitarch, C. Laguna.
Máculas pigmentadas en la mucosa oral.
Piel, 21 (2006), pp. 499-500
[116.]
N.F. Abraham, S.R. Feldman, Q. Vallejos, L.E. Whalley, T. Brooks, G. Cabral, et al.
Contact dermatitis in tobacco farmworkers.
Contact Dermatitis, 57 (2007), pp. 40-43
[117.]
R.J. Rycroft, N.P. Smith, E.T. Stok, K. Middleton.
Investigation of suspected contact sensitivity to tobacco in cigarette and cigar factory employees.
Contact Dermatitis, 7 (1981), pp. 32-38
[118.]
H. Sasaya, N. Oiso, S. Kawara, A. Kawada.
Airborne contact dermatitis from cigarettes.
Contact Dermatitis, 56 (2007), pp. 173-174
[119.]
A. Kato, A. Shoji, N. Aoki.
Contact sensitivity to cigarettes.
Contact Dermatitis, 53 (2005), pp. 52-53
[120.]
G. Dawn, C.J. Fleming, A. Forsyth.
Contact sensitivity to cigarettes and matches.
Contact Dermatitis, 40 (1999), pp. 236-238
[121.]
J.P. Rat, M. Larregue.
Contact allergy from cigarette smoking.
Allerg Immunol (Paris), 19 (1987), pp. 153-155
[122.]
G. Camarasa, A. Alomar.
Menthol dermatitis from cigarettes.
Contact Dermatitis, 4 (1978), pp. 169-170
[123.]
A.J. Bircher, H. Howald, T. Rufli.
Adverse skin reactions to nicotine in a transdermal therapeutic system.
Contact Dermatitis, 25 (1991), pp. 230-236
[124.]
I.W. Lee, S.K. Ahn, E.H. Choi, S.H. Lee.
Urticarial reaction following the inhalation of nicotine in tobacco smoke.
Br J Dermatol, 138 (1998), pp. 486-488
[125.]
A. Tosti, M. Melino, S. Veronesi.
Contact urticaria to tobacco.
Contact Dermatitis, 16 (1987), pp. 225-226
[126.]
G. Andersson, E.K. Vala, M. Curvall.
The influence of cigarette consumption and smoking machine yields of tar and nicotine on the nicotine uptake and oral mucosal lesions in smokers.
J Oral Pathol Med, 26 (1997), pp. 117-123
[127.]
W.C. Gonsalves, A.C. Chi, B.W. Neville.
Common oral lesions: Part I. Superficial mucosal lesions.
Am Fam Physician, 75 (2007), pp. 501-507
[128.]
K. Yuca, O. Calka, A.F. Kiroglu, N. Akdeniz, H. Cankaya.
Hairy tongue: a case report.
Acta Otorhinolaryngol Belg, 58 (2004), pp. 161-163
[129.]
S.L. Tomar, S. Asma.
Smoking-attributable periodontitis in the United States: findings from NHANES III. National Health and Nutrition Examination Survey.
J Periodontol, 71 (2000), pp. 743-751
[130.]
R. Wolf, E. Tur, D. Wolf.
The effect of smoking on skin moisture and on surface lipids.
Int J Cosmet Sci, 14 (1992), pp. 83-88
[131.]
C. Frances.
Smoker's wrinkles: epidemiological and pathogenic considerations.
Clin Dermatol, 16 (1998), pp. 565-570
[132.]
C.M. Lapiere, G.E. Pierard.
The mechanical forces, a neglected factor in the age-related changes in the skin.
G Ital Chir Dermatol Oncol, 2 (1987), pp. 201-210
[133.]
L.H. Kligman, A.M. Kligman.
Reflections on heat.
Br J Dermatol, 110 (1984), pp. 369-375
[134.]
L.H. Kligman.
Intensification of ultraviolet induced thermal damage by infrared radiation.
Arch Dermatol Res, 272 (1982), pp. 229-238
[135.]
A.S. Boyd, T. Stasko, L.E. King, G.S. Cameron, A.D. Pearse, S.A. Gaskell.
Cigarette smoking-associated elastotic changes in the skin.
J Am Acad Dermatol, 41 (1999), pp. 23-26
[136.]
M. Ippen, H. Ippen.
Approaches to a prophylaxis of skin aging.
J Soc Cosmetic Chemists, 16 (1965), pp. 305-308
[137.]
H.W. Daniell.
Smoker's wrinkles: a study in the epidemiology of “crow's feet”.
Ann Int Med, 75 (1971), pp. 873-880
[138.]
H.B. Allen, B.L. Johnson, S.M. Diamond.
Smoker's wrinkles?.
JAMA, 225 (1973), pp. 1067-1069
[139.]
D. Model.
Smoker's face: an underrated clinical sign?.
Br Med J, 291 (1985), pp. 1760-1762
[140.]
P. Schnohr, P. Lange, J. Nyboe, M. Appleyard, G. Jensen.
Does smoking increase the degree of wrinkles on the face? The Copenhagen City Heart Study.
Ugeskr Laeger, 153 (1991), pp. 660-662
[141.]
I. Joffe.
Cigarette smoking and facial wrinkling.
Ann Int Med, 115 (1991), pp. 659
[142.]
D.P. Kadunce, R. Burr, R. Gress, R. Kanner, J.L. Lyon, J.J. Zone.
Cigarette smoking: risk factor for premature facial wrinkling.
Ann Int Med, 114 (1991), pp. 840-844
[143.]
D. Grady, V. Ernster.
Does cigarette smoking make you ugly and old?.
Am J Epidemiol, 135 (1992), pp. 839-842
[144.]
B.E. Davis, H.K. Koh.
Faces going up in smoke. A dermatologic opportunity for cancer prevention.
Arch Dermatol, 128 (1992), pp. 1106-1107
[145.]
V.L. Ernster, D. Grady, R. Miike, D. Black, J. Selby, K. Kerlikowke.
Facial wrinkling in men and women, by smoking status.
Am J Public Health, 85 (1995), pp. 78-82
[146.]
P.M. O’Hare, A.B. Fleischer, R.B. D’Agostino, S.R. Feldman, M.A. Hinds, S.A. Rassette, et al.
Tobacco smoking contributes little to facial wrinkling.
J Eur Acad Dermatol Venerol, 12 (1999), pp. 133-139
[147.]
B. López, J. Tercedor, J.M. Ródenas, F. Simón, R.M. Ortega, S. Serrano.
Envejecimiento cutáneo y tabaquismo.
Rev Clin Esp, 195 (1995), pp. 147-149
[148.]
J.H. Chung, S.H. Lee, C.S. Youn, B.J. Park, K.H. Kim, K.C. Park, et al.
Cutaneous photodamage in Koreans. Influence of sex, sun exposure, smoking, and skin color.
Arch Dermatol, 137 (2001), pp. 1043-1051
[149.]
J.S. Koh, H. Kang, S.W. Choi, H.O. Kim.
Cigarette smoking associated with premature facial wrinkling: image analysis of facial skin replicas.
Int J Dermatol, 41 (2002), pp. 21-27
[150.]
W.C. Leung, I. Harvey.
Is skin ageing in the elderly caused by sun exposure or smoking?.
Br J Dermatol, 147 (2002), pp. 1187-1191
[151.]
C. Kennedy, M.T. Bastiaens, C.D. Bajdik, R. Willemze, R.G. Westendorp, J.N. Bouwes Bavinck.
Effect of smoking and sun on the aging skin.
J Invest Dermatol, 120 (2003), pp. 548-554
[152.]
A. Raitio, J. Kontinen, M. Rasi, R. Bloigu, J. Roning, A. Oikarinen.
Comparison of clinical and computerized image analyses in the assessment of skin ageing in smokers and non-smokers.
Acta Derm Venereol (Stockh), 84 (2004), pp. 422-427
[153.]
C. Frances.
Smoking and the skin.
Int J Dermatol, 31 (1992), pp. 779-780
[154.]
Y.R. Helfrich, L. Yu, A. Ofori, T.A. Hamilton, J. Lambert, A. King, et al.
Effect of smoking on aging of photoprotected skin: evidence gathered using a new photonumeric scale.
Arch Dermatol, 143 (2007), pp. 397-402
[155.]
C. Frances, S. Boisnic, D.J. Hartmann, B. Dautzenberg, M.C. Branchet, Y. Le Charpentier, et al.
Changes in the elastic tissue of the non-sun-exposed skin of cigarette smokers.
Br J Dermatol, 125 (1991), pp. 43-47
[156.]
M. Just, M. Ribera, E. Monsó, C. Ferrándiz.
Alteraciones de las fibras elásticas de la piel en pacientes fumadores y su relación con el deterioro de la función pulmonar.
Actas Dermosifiliogr, 95 (2004), pp. 606-612
[157.]
M. Just, M. Ribera, E. Monsó, J.C. Lorenzo, C. Ferrándiz.
Smoking effect on skin elastic fibers. Morphometric and immunohistochemical analysis.
Br J Dermatol, 156 (2007), pp. 85-91
[158.]
S.L. Mera, C.R. Lovell, R. Russell, J.D. Davies.
Elastic fibres in normal and sun-damaged skin: an immunohistochemical study.
Br J Dermatol, 117 (1987), pp. 21-27
[159.]
E.F. Bernstein, Y.Q. Chen, K. Tamai, K.J. Shepley, K.S. Resnik, H. Zhang, et al.
Enhanced elastin and fibrillin gene expression in chronically photodamaged skin.
J Invest Dermatol, 103 (1994), pp. 182-186
[160.]
C. Lahmann, J. Bergemann, G. Harrison, A.R. Young.
Matriz metalloproteinase-1 and skin ageing in smokers.
[161.]
L. Yin, A. Morita, T. Tsuji.
Skin aging induced by ultraviolet exposure and tobacco smoking: evidence from epidemiological and molecular studies.
Photodermatol Photoimmunol Photomed, 17 (2001), pp. 178-183
[162.]
M. Placzek, U. Kerkmann, S. Bell, P. Koepke, B. Przybilla.
Tobacco smoke is phototoxic.
Br J Dermatol, 150 (2004), pp. 991-993
[163.]
Just M. Las arrugas del fumador. ¿Qué hay de nuevo?. Piel. 2008. In press.
Copyright © 2008. Academia Española de Dermatología y Venereología and Elsevier España, S.L.
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